Must-see TED talks

February 18, 2013 § 5 Comments

Just a quick pop-in, both to share and bookmark these videos for myself. Skjalg and I are both obsessed with TED talks – if you don’t know about ted.com, prepare to be enlightened!

While I was getting ready for school this morning, I endulged in the following talks. I would love to take the time to explain why these were so interesting to me, but I’ll just have to let their mere presence on my blog speak for itself. The world is such a fantastically amazing place!

Alright, while you watch those, I’m off to tackle the rest of these bad boys: my biochem study plan topics for this week. Charlotte and Rina (friends from my group) and I have made a pact to send each other completed topic lists for the upcoming week every Sunday. As it is Monday, I am already behind. Can’t wait to meet my bed on the other side!

Week 3 Biochem Topics

8. Myoglobin. Structural features of the globin chain. Formula of heme, oxidation state of iron. Function of proximal and distal histidine.

10. Effect of altered amino acid sequence on protein function. Normal human hemoglobin chains, comparison of fetal form to adult forms. Abnormal human hemoglobins: neutral and harmful mutation. HgM. HbS and the sickle cell anemia.

9. Hemoglobin as an allosteric protein. Oxygen saturation curves for myoglobin and hemoglobin: a comparison. Function of BPG. The Bohr-effect and its molecular mechanism. Conformational changes during oxygenation.

11. pH and temperature dependence of enzyme activity. Effect of charged groups in the active center on the pH profiles of enzymes. Definition of enzyme activity, specific enzyme activity and turnover number. Clinical importance of enzyme assays (nonfunctional plasma enzymes).

12. Effect of the enzyme on the equilibrium and on the activation energy. Transition states. The active center of the enzymes (lock and key model, induced fit model). Acid/base and covalent catalysis.

41. Compounds of B-vitamin complex, Vitamin C and their biological roles. Thiamine, riboflavine, pyridoxine, cobalamine and their coenzyme derivatives.

42. Vitamins belonging to nucleotides (CoA, NAD(P), FAD). Their role as coenzymes in the hydrogen or acyl group transfer. Other water soluble vitamins (folic acid, biotin). Their structure and function as coenzymes.

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